Rohan is a young student who dreams of becoming a mangaka. His life changes the day he meets a young woman who introduces him to the world of art. She tells him about sculpture, music, and painting - particularly a "cursed painting" by a Japanese artist long ago acquired by a curator at the Louvre. Then the young woman suddenly disappears.

Ten years later, Rohan, now a mangaka, decides to conduct his own investigation at the Louvre to find the painting that just might lead him to the young woman. But he discovers strange phenomena: does approaching the painting mean death? What does it represent? What is its secret?

Rohan at the Louvre is the first manga in the comic-art collection published by Musée du Louvre Editions.